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Smad2

Recombinant Smad2 Protein - Professional Protein Supplie

Mothers against decapentaplegic homolog 2 also known as SMAD family member 2 or SMAD2 is a protein that in humans is encoded by the SMAD2 gene. MAD homolog 2 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that. SMAD2 gene SMAD family member 2. Open All Close All. The information on this page was automatically extracted from online scientific databases. Normal Function. From NCBI Gene: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are. SMAD2 mediates the signal of transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes—e.g., cell proliferation, apoptosis and differentiation. In response to the binding of TGF-beta, SMAD2 is phosphorylated and dissociated from the SMAD anchor for receptor activation (SARA) protein and forms a complex with SMAD4, resulting in transcription regulation

Eigenschaften. Der Name leitet sich vom homologen Gen der Taufliege Drosophila melanogaster, MAD (engl. mothers against decapentaplegic) und dem Gen für das Protein Sma (engl. small body size ‚kleine Körpergröße') des Fadenwurms Caenorhabditis elegans ab.. Klassen. Die Rezeptor-regulierten SMAD (R-SMAD, SMAD1-3, -5, -8, -9) Der common-mediator-SMAD4 (co-SMAD), der mit R-SMAD interagier SMAD2 single nucleotide polymorphism rs11082639 is associated with metabolic syndrome in a Taiwanese population. TGIF1 homeodomain interacts with Smad2/Smad4 MH1 domains and represses TGF-beta signaling. the crucial role played by Smad2 in promoting Mst1-mediated cell apoptosis and mitochondrial stress, is reported SMAD2 (SMAD Family Member 2) is a Protein Coding gene. Diseases associated with SMAD2 include Osteopoikilosis and Melorheostosis.Among its related pathways are Metabolism of proteins and Th1 Differentiation Pathway.Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and transcription factor binding

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SMAD (protein) - Wikipedi

Mothers against decapentaplegic homolog 2 - Wikipedi

SmadAV 2020 is a freeware antivirus software app filed under antivirus and made available by SmadAV for Windows. The review for SmadAV 2020 has not been completed yet, but it was tested by an editor here on a PC. If you would like to submit a review of this software download, we welcome your input and encourage you to submit us something! A secondary antivirus application from overseas. Most. DISEASE ASSOCIATED WITH smad2 HUMAN ORTHOLOG No data available. DISEASE ASSOCIATED WITH smad2 VIA EXPERIMENTAL MODELS No data available. GENE ONTOLOGY Ontology GO Term; Biological Process regulation of transcription, DNA-templated Cellular Component nucleus. SMAD2 Gene Set. Dataset: CHEA Transcription Factor Targets: Category: genomics Type: transcription factor: Description: SMAD family member 2|The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional. SMAD2 Antibodies . SMAD2 (MADH2, MAD2) regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. SMAD2 interacts with the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation into the nucleus is a central event in TGF beta signaling. Phosphorylation of threonine 8 in the calmodulin-binding region of the MH1 domain by.

SMAD2 gene - Genetics Home Reference - NI

  1. SMAD2. Addgene Alerts Receive email alerts when new plasmids with this gene become available. Log in to subscribe to Addgene Alerts. Description SMAD family member 2 Also known as JV18, JV18-1, MADH2, MADR2, hMAD-2, hSMAD2 Species Homo sapiens Entrez ID 4087. MGC.
  2. Smad2 Gene Detail Summary Symbol. Smad2 Name. SMAD family member 2. Synonyms. 7120426M23Rik, Madh2, Madr2, Smad 2 Feature Type. protein coding gene. IDs. MGI:108051 NCBI Gene: 17126. Alliance. gene page. Transcription Start Sites. 6 TSS. Location & Maps more. Sequence Map Chr18:76241580-76310963 bp, + strand From Ensembl annotation of GRCm38. View this region in JBrowse: Genome Browsers.
  3. SMAD3 (SMAD Family Member 3) is a Protein Coding gene. Diseases associated with SMAD3 include Loeys-Dietz Syndrome 3 and Familial Thoracic Aortic Aneurysm And Dissection.Among its related pathways are Metabolism of proteins and Th1 Differentiation Pathway.Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and sequence-specific DNA binding
  4. 关于SMAD2: Smads家族是转化生长因子TGF-β信号转导途径中一个重要的新基因家族。SMAD2属于受体激活的SMADs。Smad2基因在多种肿瘤中发生突变,是一种可能的肿瘤抑制基因
  5. Smad蛋白,Smads蛋白(drosophila mothers against decapentaplegic protein)家族: Smads家族蛋白在将TGF-β信号从细胞表面受体传导至细胞核的过程中起到关键性作用,且不同的Smad介导不同的TGF-β家族成员的信号转导。TGF-β作为配体形成的受体复合物,激活Smads进入核内,共同激活或抑制它们调节的靶基因的转录

Smad2: Products. Smads are a family of intracellular proteins that mediate signaling by members of the TGF-beta superfamily. Smads are divided into three distinct subgroups based on their different roles in TGF-beta family signal transduction: R-Smads (receptor-regulated), Co-Smads (common partner), and I-Smads (inhibitory) Smad2 antibody wu:fj43c06 antibody Xmad2 antibody XSmad2 antibody Protein level used designations for SMAD2 MAD homolog 2 , SMAD, mothers against DPP homolog 2 , Sma- and Mad-related protein 2 , mother against DPP homolog 2 , mothers against decapentaplegic homolog 2 , SMAD 2 , mothers against DPP homolog 2 , mothers against decapentaplegic-like 2 , MAD (mothers against decapentaplegic.

SMAD2 definition of SMAD2 by Medical dictionar

  1. P84022: Protein family/group databases MoonDB i: P84022 Predicted: Names & Taxonomy i. Protein names i: Recommended name: Through the action of the phosphatase PPM1A, released from the SMAD2/SMAD4 complex, and exported out of the nucleus by interaction with RANBP1 (PubMed:16751101, PubMed:19289081). Co-localizes with LEMD3 at the nucleus inner membrane (PubMed:15601644). MAPK-mediated.
  2. Rabbit recombinant monoclonal Smad3 (phospho S423 + S425) antibody [EP823Y]. Validated in WB, ELISA, IHC, Dot, ICC/IF and tested in Mouse, Human, Drosophila melanogaster. Cited in 235 publication(s
  3. SMAD-Protein - Wikipedi
  4. 4087 - Gene ResultSMAD2 SMAD family member 2 [ (human)
  5. SMAD2 Gene - GeneCards SMAD2 Protein SMAD2 Antibod
  6. SMAD2 - Mothers against decapentaplegic homolog 2 - Homo
  7. Smad蛋白_百度百科 - baike

Video: Constitutively Active SMAD2/3 Are Broad - Cell Stem Cel

Video: SMAD2 SMAD family member 2 - Gene - GTR - NCB

Video: CST - Phospho-Smad2 (Ser465/467)/Smad3 (Ser423/425) (D27F4

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